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人材・研究費助成公募
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人材公募 >> コンテンツ詳細
公募内容 Postdoctoral Position in Molecular Neurophysiology(Duke-NUS)
応募締め切り
募集人員
 Duke-NUS Graduate Medical School in Singapore
The laboratory of Molecular Neurophysiology (Dr. Shawn Je) at Duke-NUS Graduate Medical School in Singapore is seeking talented and motivated postdoctoral candidates who love science and are fascinated by synapses, dendrites, neural circuits, and the remarkable cell biology of neurons. We are particularly interested in candidates who have a strong background in in vitro electrophysiology with an interest in applying physiological techniques toward cell biological questions in synapse function. Current projects range from cultured dissociated neurons to brain slices to in vivo recording. Interested candidates should submit a curriculum vitae and contact information for three references to:
    

Shawn Je, Ph.D.

Program in Neuroscience and Behavioral Disorders
Duke-NUS Graduate Medical School
8 College Road, Singapore, 169857

email: shawn.je@duke-nus.edu.sg, je@neuro.duke.edu
http://research.duke-nus.edu.sg/nbd/index.php?option=com_profile&task=detail&cid=13&Itemid=0
提出書類
問合せ・応募先
その他

Selected publications

Je, H.S., Yang, F., Potluri, S., Ji, Y., Nagappan, G., Hempstead, B., Son, Y.J., and Lu, B. (2011) Role of proBDNF to Mature BDNF Conversion in Activity-dependent Competition at Developing Neuromuscular Synapses. Manuscript under revision in Nature Neurosci.

Wang, X., McCoy, P.A., Rodriguiz, R.M., Pan, Y., Je, H.S., Roberts,A.C., Kim, C., Berrios, J., Colvin, J.S., Bousquet-Moore, D., Lorenzo, I., Wu, G., Weinberg, R.J., Ehlers, M.D., Philpot, B.D., Beaudet, A.L., Wetsel, W.C., and Jiang, Y. (2011) Synaptic dysfunction and abnormal behaviors in mice lacking the major isoforms of Shank3. Human Molecular Genetics (in press).


Je, H.S. *, Ji. Y. *, Wang, Y., Yang, F., Wu, W., and Lu, B. (2011) Presynaptic protein synthesis required for NT-3-induced long-term synaptic modulation. Molecular Brain, 4:1. *: co-first authors.


Jiang, Z., Belforte, J., Lu, Y., Yabe, Y., Pickel, J., Smith, C., Je, H.S., Lu, B., and Nakazawa, K. (2010) eIF2alpha phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memoryconsolidation without affecting general translation. J. Neurosci.30, 2582-94.


Je, H.S.*, Lu, Y.*, Yang, F., Nagappan, G., Zhou, J., Jiang, Z., Nakazawa, K., and Lu, B. (2009) Chemically Inducible Inactivation of Protein Synthesis in Genetically Targeted Neurons. J. Neurosci. 29, 6761-16. *: co-first authors.


Yang, F.*, Je, H.S.*, Ji, Y., Nagappan, G., Hempstead, B., and Lu, B.(2009) ProBDNF-induced Synaptic Depression and Retraction at Developing Neuromuscular Synapses. J. Cell Biol. 185, 727-41. *: co-first authors. Highlighted in: 1) BDNF sends mixed signals, J. Cell Biol. (2009)185:566 2) Faculty of 1000, 23 Jun 2009. F1000.com/1162040


Lu, Z., Je, H.S., Young, P., Gross, J., Lu, B., and Feng, G. (2007) Regulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junction. J. Cell Biol.18, 1077-89. Highlighted in: Faculty of 1000 Biology, 9 Aug 2007. F1000.com/1088748


Je, H.S., Yang, F., Zhou, J., and Lu, B. (2006) Neurotrophin 3 induces structural and functional modification of synapses through distinct molecular mechanisms. J Cell Biol. 18, 1029-42.


Je, H.S., Zhou, J., Yang, F., and Lu, B. (2005) Distinct mechanisms for neurotrophin-3-induced acute and long-term synaptic potentiation. J. Neurosci. 14, 11719-29.


Luo, Z.G., Je, H.S., Wang, Q., Yang, F., Dobbins, G.C., Yang, Z.H., Xiong, W.C., Lu, B., and Mei, L. (2003). Implication of geranylgeranyltransferase I in synapse formation. Neuron. 13, 703-17. Highlighted in: Faculty of 1000 Biology, 12 Dec 2003. F1000.com/1016586


Du, J., Feng, L., Zaitsev, E., Je, H.S., Liu, X.W., and Lu, B. (2003). Regulation of TrkB receptor tyrosine kinase and its internalization by neuronal activity and Ca2+ influx. J. Cell Biol. 27, 385-95. Wang, C.Y., Yang, F., He, X.P., Je, H.S., Zhou, J.Z., Eckermann, K.,


Kawamura, D., Feng, L., Shen, L., and Lu, B. (2002). Regulation of neuromuscular synapse development by glial cell line-derived neurotrophic factor and neurturin. J. Biol. Chem. 22, 10614-25.
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記入者:林：DB委員会事務